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Strive to Buy Semler in All-Stock Deal, Growing BTC Holdings

Key Highlights: 

  • Strive Asset Management is set to acquire Semler Scientific in an all-stock deal.
  • After the closure of the deal, the company will hold more than 10,900 Bitcoins.
  • The transaction will position Strive as one of the largest corporate holder of Bitcoin in the U.S.

Bitcoin’s rising role in the U.S. financial markets continues as Strive Asset Management ($ASST), co-founded by former presidential candidate Vivek Ramaswamy, has signed a definitive agreement to buy Semler Scientific ($SMLR) in an all-stock deal. This transaction clearly shows the corporate shift to Bitcoin, which is boosting Strive’s presence in asset management while combining its institutional scale with Semler’s active Bitcoin treasury strategy.

Matt Cole, CEO at Strive shares the shares recent updates

The acquisition was confirmed today September 22, 2025, making Strive one of the U.S. companies with a huge Bitcoin holdings. After the merger, Strive and Semler will together hold more than 10,900 Bitcoins. This huge number will place the company close to Strategy (formerly known as MicroStrategy) and other major firms following aggressive Bitcoin accumulation strategies.

Transaction Details

Strive shared a detailed update on the agreement, confirming it will acquire Semler Scientific through an all-stock merger. The company has already purchased 5,816 Bitcoin as a part of its Bitcoin treasury strategy. Together, as stated above, the entity will control over 10,900 BTC after the merger. Eric Semler, President of Semler Scientific, will join Strive’s board after the deal is closed. The company is also planning to either sell or distribute Semler’s profitable diagnostic business, which was the company’s main operation before it shifted its focus to Bitcoin.

Semler’s Bold Bitcoin Pivot

Semler Scientific has made headlines in 2024 for being the first mid-size medical tech company that focused its brand on Bitcoin. The California company moved its treasury to Bitcoin, and left its diagnostics device business behind. This shift attracted investors wanting direct Bitcoin exposure through U.S. stocks, similar to MicroStrategy. Strive noticed Semler because it supports shareholder-first strategies and alternative ways to use company assets.

Vivek Ramaswamy’s Vision

For Ramaswamy, the acquisition is not just a deal , it is a statement. The former presidential candidate has now positioned Strive to compete with Wall Street giant like BlackRock, and it is focusing more on giving shareholder the most value instead of following political investment ideas.

“The acquisition of Semler Scientific shows Strive’s belief in Bitcoin as a treasury reserve and key store of value,” Ramaswamy said. “Together, we will promote a bold model of institutional Bitcoin use while keeping shareholder choice for legacy assets like Semler’s diagnostics business.”

Market Significance

The merger makes Strive one of the biggest corporate holders of Bitcoin, showing that it is a major Bitcoin adopter in the U.S. The all-stock deal lets Strive invest in Bitcoin without spending cash right away. Adding Eric Semler to the board will keep Semler’s vision alive and intact. Analysts say that selling or spinning off the diagnostic business could give extra value to shareholders, while keeping Bitcoin as the main focus of the company.

Wall Street’s Bitcoin Moment

The merger has come at a time when Wall Street is embracing Bitcoin big time. The launch of U.S. spot Bitcoin ETFs has also increased institutional adoption of cryptocurrencies, while companies like Strategy and Tesla continue to grow their BTC holdings. With more than 10,900 Bitcoin after this merger, Strive-Semler is now among the top public companies by BTC reserves, cementing Bitcoin’s role as a key balance sheet asset in corporate America.

Industry observers are expecting this deal to increase such mergers and acquisitions from asset managers and companies with weaker core businesses but strong Bitcoin positions, marking a significant moment for the market.

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Harsh Chauhan: Harsh Chauhan is an experienced crypto journalist and editor at CryptoNewsZ. He was formerly an editor at various industries, including his tenure at TheCryptoTimes, and has written extensively about Crypto, Blockchain, Web3, NFT, and AI. Harsh holds a Bachelor of Business Administration degree with a focus on Marketing and a certification from the Blockchain Foundation Program. Through his writings, he holds the pulse of the rapidly evolving crypto landscape, delivering timely updates and thought-provoking analysis. His commitment to providing value to readers is evident in every piece of content produced. With a deep understanding of market trends and emerging technologies, he strives to bridge the gap between complex blockchain concepts and mainstream audiences.